PRK (Photorefractive Keratectomy) laser eye surgery

PRK (PhotoRefractive Keratectomy) is a laser refractive surgery technique used to correct short-sightedness (myopia), long-sightedness (hyperopia), and astigmatism by reshaping the surface of the cornea.

Unlike LASIK, it does not require the creation of a corneal flap. Instead, the epithelium (the thin outer layer of the eye) is temporarily removed to allow the excimer laser to precisely sculpt the underlying corneal tissue. This "surface-based" method is particularly suitable for patients with thin or irregular corneas, offering excellent long-term visual stability.

How does it work?

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This illustration shows a complete eye in cross-section, viewed from the side, in a horizontal position as in a person standing upright.

The cornea, located at the front, is highlighted in green. This is the transparent part of the eye.

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This diagram only shows the cornea in cross-section, represented in a vertical position as if lying on your back.

First step of PRK: removal of the superficial epithelial layer of the cornea. This thin protective layer is removed either mechanically, often with the help of a diluted alcohol solution, or directly with the laser in the case of TransPRK, in order to expose the underlying stroma for laser ablation.

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Second step of PRK: ablation of the underlying corneal stroma using the excimer laser. The laser precisely reshapes the corneal curvature to correct the visual defect, according to the prescription and, where applicable, topographic or aberrometric data.

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A therapeutic contact lens is placed on the treated cornea to protect the surface, promote epithelial regeneration and reduce discomfort during healing.

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The epithelium gradually regenerates from the edges of the defect, covering the laser-treated area. This regeneration restores the corneal surface within a few days.

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Healed cornea after PRK: the corneal surface is smooth, clear and even, with a fully regenerated epithelium. Vision is now corrected, allowing clear sight without glasses or contact lenses.

Content

What is PRK?

PRK (PhotoRefractive Keratectomy) is a laser vision correction used to treat short-sightedness (myopia), long-sightedness (hyperopia), and astigmatism.

It works by reshaping the surface of the cornea to improve how light focuses on the retina. Unlike LASIK, PRK does not involve the creation of a corneal flap, making it an ideal choice for patients with thin corneas or superficial corneal scars. While the final visual outcomes are comparable to LASIK and SMILE, the initial recovery period is slightly longer.

How does PRK work?

  1. Preparation: Topical anaesthetic drops are applied to numb the eye. A small, gentle speculum is used to keep the eyelids open, ensuring a stable and precise procedure.
  2. Epithelium Removal: The thin outer layer of the cornea (the epithelium) is removed to expose the underlying tissue. This can be done mechanically, with a specialized diluted alcohol solution, or directly via the laser (TransPRK).
  3. Corneal Reshaping: An Excimer laser uses "cold" ultraviolet light to remove microscopic amounts of tissue:
    1. For short-sightedness: The cornea is flattened.
    2. For long-sightedness: The cornea is made steeper.
    3. For astigmatism: The laser smooths the cornea into a more spherical shape.
  4. Healing: The epithelium regenerates naturally over the following days. A bandage contact lens is placed over the eye to protect the surface, facilitate healing, and minimise discomfort.
  5. Results: Vision improves progressively. Functional recovery typically takes 1 to 2 weeks, with final stabilization usually achieved within 3 months.

Advantages of PRK

  • No Flap Complications: Eliminates risks such as flap displacement, folds (striae), or epithelial ingrowth.
  • Suitable for Thin Corneas: The preferred option for patients whose corneas are too thin for LASIK or SMILE.
  • Proven Reliability: Final visual results are generally excellent and equal to those of LASIK and SMILE.
  • Ideal for Contact Sports: Because there is no flap, SMILE and PRK are recommended for athletes in combat sports or professions with a high risk of ocular trauma.

Who is a suitable candidate?

  • Thin or Irregular Corneas: A safe alternative when other laser methods are not recommended.
  • Active Lifestyles: Ideal for military personnel, athletes, or those in high-impact occupations.
  • Stability: A stable prescription for at least 1–2 years is the primary criterion.
  • General Health: Candidates should be in good health, with no uncontrolled autoimmune conditions or significant ocular diseases like advanced cataracts or keratoconus.
  • Pregnancy: Candidates should not be pregnant or breastfeeding.

What are the risks of PRK?

PRK is a highly established and safe procedure, though it involves a unique healing process:

  • Discomfort: Temporary eye pain or a "gritty" sensation is expected during the first 3–5 days while the epithelium regrows.
  • Visual Fluctuations: Blurred vision or fluctuations are normal for several weeks as the new surface smooths over the treatment zone.
  • Dry Eye: Temporary dryness is common; it is managed with lubricating drops.
  • Corneal Haze: This refers to a slight "cloudiness" or irregular healing of the cornea, particularly in cases of high corrections. This is generally prevented by the application of Mitomycin C (MMC) during surgery. If haze does occur, it may be managed with specific post-operative treatments, such as Losartan eye drops.
  • Persistent Epithelial Defect (PED): On rare occasions, the surface layer may take longer than usual to heal. This delayed healing can be treated with specialized interventions, such as insulin eye drops or the application of a healing (bandage) contact lens.
  • Infection: Extremely rare (<1 in 10,000) and typically detected early through close post-operative monitoring during the epithelial regeneration phase.
  • Corneal Ectasia: An exceptionally rare weakening of the cornea. Proper patient selection and the avoidance of eye rubbing (friction) are essential to prevent this.
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