Topography-guided or wavefront-guided PRK

Topo- or wavefront-guided PRK (Photorefractive Keratectomy guided by corneal topography or total optical aberrations) is an advanced refractive surgery technique that corrects visual anomalies by relying on the corneal map or the eye's complete wavefront. It is particularly indicated for patients with corneal irregularities, such as scars or asymmetries inducing higher-order aberrations.

Arthur Hammer
Ophthalmic Surgeon, specializing in cornea, cataract, and refractive surgery

How does it work?

Learn more about the procedure / equipment

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Cornée irrégulière traitée par PRK customisée (topo- ou wavefront-guidée): la surface cornéenne initialement déformée, avec zones asymétriques ou irrégulières, est progressivement régularisée par le laser excimer.

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Œil juste après une PRK customisée: la cornée présente un défect épithélial central, correspondant à la zone traitée par le laser. Une lentille de contact thérapeutique est placée sur l’œil pour protéger la surface, favoriser la cicatrisation et réduire l’inconfort postopératoire.

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L’épithélium se régénère progressivement à partir des bords du défect, recouvrant la zone traitée au laser. Cette régénération permet de restaurer la surface cornéenne en quelques jours.

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Cornée cicatrisée après une PRK customisée: l’épithélium s’est régénéré de manière plus uniforme avec une cornée plus lisse et homogène, réduisant les aberrations visuelles et améliorant la qualité optique.

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Principle and Procedure

Topo- or wavefront-guided PRK follows the same general steps as conventional PRK, but with increased precision thanks to the use of an excimer laser guided by the patient's individualized topographic data.

  1. Corneal Preparation : the superficial epithelial layer is removed either mechanically, sometimes with the aid of a diluted alcoholic solution, or directly by laser when it is a TransPRK, combining PRK with a type of epithelial ablation TransPTK.
  2. Topography-Guided Ablation : the excimer laser precisely reshapes the cornea according to data collected by topography or ocular aberrometry. This approach aims to homogenize the corneal surface and improve overall optical quality.
  3. Combination with corneal cross-linking (CXL) : custom PRK can be performed at the same time as CXL to regularize the corneal surface in cases of ectasia, such as keratoconus, while stabilizing the corneal structure.
  4. A bandage/therapeutic contact lens is placed to improve comfort and promote epithelial regeneration, which usually takes a few days.

Goal

  • Improved visual quality through a reduction in corneal irregularity and optical aberrations.
  • Can be used in the same way as refractive PRK to reduce dependence on glasses, while also improving visual quality.
  • Regularization of highly irregular or ectatic corneas (e.g., keratoconus) to:
    • Improve the quality of vision with glasses
    • Preparation before implantable contact lens (ICL/IPCL) surgery
    • Preparation before cataract surgery

Indications

  • Irregular astigmatism
  • Superficial scars or corneal irregularities
  • Vision optimization after previous imperfect refractive treatment
  • Keratoconus (in association with CXL)

Advantages

  • Improvement of visual quality and reduction of optical aberrations
  • Personalized treatment based on the corneal topography or the aberrometric profile unique to each eye, for a customized visual correction.

Limitations

  • Slower recovery than with LASIK or SMILE.
  • Post-operative discomfort during the first few days (alleviated by wearing a therapeutic contact lens).
  • Risk of transient corneal haze; however, eye drops are now available (Losartan) to fade scars.

Possible Risks and Complications

These are the same risks as for PRK.

Les différentes types de greffes

Découvrez les kératoplasties (= greffes de cornée)

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Frequently asked questions

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